TMBC Monthly Newsletter, April 2017, V5

Every month The Microbiome Coalition (TMBC) will bring you the latest in research, news and information to keep you up to date on the microbiome industry.

We welcome your feedback and suggestions for content.

Microbiome in the Spotlight

George Church is world renowned for his work in the precision medicine space, but he is now bringing his own personal touch to the microbiome, asking "What if we could tap the gut bacteria of elite athletes to produce customized probiotics ― and what if those probiotics could give recipients access to some of the biological advantages that make those athletes elite?" We buy their branded sneakers, branded clothes, branded training programs - why not the most personal thing that may give them an athletic advantage? In an era where we happily ingest enormous quantities of sports drinks, protein powders, branch chain amino acids in the quest for better performance, why not something even more specific to athletic performance? Is this a step too far? Read more here

In the News

Link between microbiome in the gut, Parkinson's discovered
There is growing evidence showing a connection between Parkinson's disease -- a neurodegenerative condition -- and the composition of the microbiome of the gut. A new study from researchers at the University of Alabama at Birmingham shows that Parkinson's disease, and medications to treat Parkinson's, have distinct effects on the composition of the trillions of bacteria that make up the gut microbiome. Full article here

CU Cancer Center and CSU Trial Shows Rice Bran Promotes Microbiome Diversity, Slows Growth of Colorectal Cancer Cells
University of Colorado Cancer Center researchers at Colorado State University presented results of a phase II clinical trial of 29 people exploring the effects of adding rice bran or navy beans to the diets of colorectal cancer survivors. Full article here

Study links changes in oral microbiome with metabolic disease
A team of scientists from The Forsyth Institute and the Dasman Diabetes Institute in Kuwait have found that metabolic diseases, which are characterized by high blood pressure, high blood sugar, and obesity—leads to changes in oral bacteria and puts people with the disease at a greater risk for poor oral health. Full article here

Finch Therapeutics Announces Strategic Collaboration with OpenBiome to Develop Microbiome Therapies for FDA Approval
Finch Therapeutics, Inc., a microbiome therapeutics company, and OpenBiome, a leading public stool bank, today announced a collaboration to develop FIN-403, an orally administered microbial therapy for approval by U.S. Food and Drug Administration (FDA) in recurrent C. difficile infections. Full article here
(OpenBiome is on a roll this Spring, Takeda has also announced a collaboration with the growing start-up, learn more here)

Microbiome study finds children with type 2 diabetes more likely to have poor oral health
The first study of oral health in children with type 2 diabetes, including those who are obese, has found that these children tend to have poorer oral health than children who do not have type 2 diabetes. Published earlier this month in PLOS One, the study of three groups of children – 19 normal weight children, 14 obese children and 16 obese children with type 2 diabetes –found that poor oral health is more common in obese children with type 2 diabetes. The age range for all groups was 10-19. Full article here

Penn Vet launches new platform to accelerate microbiome research

The School of Veterinary Medicine’s Center for Host-Microbial Interactions (CHMI) has now launched a powerful new online resource to help researchers and clinicians navigate these vast quantities of microbiome-related data, providing tools to help mine the data to identify associations that can then motivate hypothesis-driven research. Full article here

Conference Highlight

Arrowhead 3rd Annual Translational Microbiome Conference, April 11-13, Boston
Arrowhead continues to focus on and address the challenges and hurdles that companies working in the microbiome space must recognize and navigate in order to successfully commercialize their products. With a broad focus spanning multiple disease states (oncology, dermatology, inflammatory disorders, among others) attendees will have the opportunity to hear the leading companies discuss the work they have underway and how they are meeting these challenges head on to apply recent discoveries to a variety of disease processes, restoration of health and improved outcomes. Conference website here

Microbiome Awards, Fellowships and Prizes

Stand Up to Cancer innovation grant funds MD Anderson microbiome study

n Innovative Research Grant from Stand Up to Cancer will help a University of Texas MD Anderson Cancer Center physician scientist and her team understand how the bacteria in the digestive tracts of melanoma patients affects their response to a common immunotherapy drug. The $750,000, three-year grant to Jennifer Wargo, M.D., associate professor of Surgical Oncology and Genomic Medicine, is one of 10 nationally announced at the annual meeting of the American Association for Cancer Research. Full article here

The Microbiome Coalition (TMBC) |

Promoting Greater Understanding of the Role of the Microbiome in Human Health and Wellness