TMBC Monthly Newsletter, July 2017, V8

Every month The Microbiome Coalition (TMBC) will bring you the latest in research, news and information to keep you up to date on the microbiome industry.

We welcome your feedback and suggestions for content.

Microbiome in the Spotlight

Alterations of the Gut, Manifested in the Brain

The idea that an ulcer might not be caused by stress and spicy food but rather by a bacteria, an idea posited in the 1980's by Nobel Prize winner Dr. Barry Marshall (who ultimately drank a broth containing H. pylori to prove his hypothesis) will hopefully make it easier to accept that other diseases may have their genesis in the gut. Recent research conducted at the Karolinska Institute in Sweden suggests that Parkinson's disease may start in the gut and be carried to the brain via the vagus nerve, which controls unconscious body processes like heart rate and food digestion. Full article here. And be sure to check out the possible implication of gut bacteria on another brain disorder in the New Mexico population, and on COPD, in In Research News below.


In Business News

Nestle Health Sciences Invests in Joint Venture with Enterome to Develop Microbiome Dx  

The company long known for its chocolates continues to increase its reach into the healthcare space, started with its entry into the precision medicine space with the acquisition of Prometheus labs in 2011, by creating a joint venture with French start-up Enterome to create microbiome based diagnostics for inflammatory bowel and liver disease. Full press release here

APC Microbiome Institute Launches Mind Your Microbes App for Children
Funded by a Discover Grant from Science Foundation Ireland, the APC Microbiome Institute at University College Cork aims to educate children about the role and importance of the human microbiome, for a national and international audience. Full article here

DayTwo Secures $12M from J&J for Personalized Nutrition Based on Microbiome

DayTwo is the first company to develop a method to accurately predict an individual's glycemic response to specific foods and food combinations using an individual's microbiome and other clinical factors. This evidence-based approach to nutrition is based on research by Professors Eran Segal and Eran Elinav from the Weizmann Institute of Science in Israel. Full article here 

Locus Biosciences Secures $5M Investment for Use of CRISPR Technology in Microbiome Therapies

The identification of CRISPR technology, a simple yet powerful tool for editing genomes, allowing researchers to easily alter DNA sequences and modify gene function,is causing substantial buzz in the cancer field. But Locus Biosciences hopes to use the same technology to advance multiple infectious disease product programs targeting antibiotic resistant infections and other microbiome-related diseases. Full article here

Biotia Aims to Cut Hospital-Acquired Infections by Monitoring Microbiome of Hospital Environment

Last month we reported on the results of the year long study of the hospital biome completed by Dr. Jack Gilbert and its impact on human health. New York startup Biotia aims to help hospitals cut down on infections by providing them with a DNA sequencing-based microbial surveillance service and targeted interventions. Full article here


In Research News

Specific Gut Bacteria May Trigger Brain Disease in Population with Specific Genetic Mutation

Cavernous cranial malformation or CCM is caused by a genetic mutation and is particularly prevalent amongst the New mexico population. A recent study co-authored by Dr. Leslie Morrison, a University of New Mexico physician, suggests that a specific bacteria in the gut is responsible for whether or not the mutation is triggered. Full article here 

Specific Lung Bacteria, and Sub-Type of COPD, May Influence Structural Change to the Lungs

Expected to be the third leading cause of death worldwide by 2030, bacterial changes in the lungs of COPD patients with structural changes may be used to identify proper treatment options, according to research by Dr. Marion Engel a scientist in the German Research Center for Environmental Health. Full article here

Was Mom Wrong About Neosporin?

Neosporin and bandaids for cuts and scrapes go together like peanut butter and jelly, but perhaps the is that Neosporin doing more harm than good by broadly disrupting the skin biome? Researchers from the University of Pennsylvania Perelman School of Medicine looked at the impact of the use of broad spectrum neomycin based topical antibiotics and discovered a broad disruption of the skin biome lasting well over a week after treatment. Full article here

Chicken or Egg: Diabetes and Oral Health or Oral Health and Diabetes?

Last month we reported on research suggesting that children with diabetes are prone to poor oral health, that article here. But what if diabetes actually causes a change in the oral microbiome resulting in a bacterial composition that is more pathogenic, causing more inflammation in the gums and greater loss of bone around the teeth? Full article here

The Ocular Surface: Not a Sterile Environment and Bacteria May Play Significant Role in Immune Responses. 

Contrary to previous belief that the ocular surface was sterile due in large part to the presence of the lysozyme enzyme which eliminates bacteria, new research suggests microbes living on human eyes are important for healthy immune responses, protecting the eyes against infection. Full article here

In Member News

Reckitt Benckiser to Acquire Mead Johnson Nutrition

Reckitt Benckiser a global leader in the consumer goods space announces plans to acquire Mead Johnson Nutrition, representing a significant step forward in RB’s journey as a global leader in consumer health and its entry into the microbiome space. Press release here

Jobs Board

Assistant Marketing Intern, The Microbiome Coalition (TMBC) 

The Microbiome Coalition (TMBC) is a newly launched coalition of commercial companies that seek to promote greater public understanding of the role of the microbiome in human health and wellness, and works to advance appropriate regulation, needed investment and required infrastructure. TMBC is seeking an Assistant Marketing Intern to play a crucial role in developing and growing the visibility and size of the organization. This internship will give you real marketing experience. If interested, get in touch here

NIH Funded PostDoc in AhR, Microbiome, and Autoimmunity, University of Missouri School of Medicine

An NIH-funded postdoctoral position is currently available immediately to study the influence of the environment on the cellular and molecular mechanisms governing the differentiation and function of CD4 T lymphocytes and their role in immunity and tolerance. Learn more here

Senior Director, Bioprocess Development, Seres Therapeutics, Cambridge, MA

As the Senior Director, Bioprocess Development, you will have an opportunity to develop world-class bioprocesses, formulations, and analytics for the manufacture of our microbiome therapeutics. Learn more here

Microbiome Research Investigator, Novartis Institutes for Biomedical Research

NIBR is seeking an innovative scientist to join a drug discovery program in the area of human microbiome research. The successful candidate will work in a dynamic new discovery department named Chemical Biology and Therapeutics (CBT) that aspires to discover and create new types of small molecules- and biomolecules- to  identify new targets, to dissect human biology and address key unmet medical needs associated with dysregulation of the microbiome. Learn more here


Upcoming Conferences

Microbiome: Translating into Diagnostics and BioTherapeutics Summit

The Summit will shed light on current challenges, best practices, and the inside view of the future of Microbiome in relation to precision medicine, Sept 21-22, Vienna, Austria,

Microbiome in Immune Oncology

Understanding the relationship between the human microbiome and cancer could be instrumental in transforming immune-modulating therapies, since a certain immunotherapy is reliant on the gut’s microflora, Sept 25, Boston, MA,

5th Microbiome R&D & Business Collaboration Forum

This two-day, interactive meeting, will provide the opportunity to examine the latest research into microbial communities with a focus on translation to therapeutics. San Diego, Nov 2-3, 

Keystone Symposia, Microbiome in Health and Disease

This Keystone Symposia meeting brings together experts in clinical medicine, clinical microbiology, microbial genomics, and bacterial genetics to explore how both strain variation and underlying microbial community determine health and disease. Keystone, CO, Feb 5-9,


Microbiome Awards, Fellowships and Prizes

Mo-Bio Laboratories Microbiome Awards Qiagen announced the opening of the 2017 Microbiome Awards, which aim to provide extraordinary scientists with products and recognition to carry out scientific work in the field of microbiome research. Full press release here


TMBC Membership

Consider joining the coalition. Members of TMBC participate on our committees, attend our events, generate networking and business development opportunities and, most importantly, contribute to the growth and success of a unique organization that is positioned to ensure that public opinion and policy pave the way for microbiome based therapeutics, diagnostics and direct-to-consumer services and products.

Membership Categories

• Sole proprietor (legal, consulting, other)  • Academic and clinical institutions
• Patient advocacy groups  • Industry/trade associations  
• Corporations (pharmaceutical, diagnostic,bioinformatics, other)

Benefits of Membership

• Shape the Future of Microbiome Policy • Curated research library
• Monthly newsletter • White papers • Extended network • Job listings • Event listings

See our flyer for more details

The Microbiome Coalition (TMBC) |

Promoting Greater Understanding of the Role of the Microbiome in Human Health and Wellness